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Salivary Gland Dysfunction

Salivary Gland Dysfunction


Salivary gland dysfunction, also known as salivary gland disorder or salivary gland disease, refers to a group of medical conditions that affect the production, flow, or composition of saliva.

Saliva & Salivary Gland

The salivary glands are a group of glands that produce saliva. Saliva is a clear, watery fluid that helps to:

  • Moisten the mouth and throat

  • Cleanse the mouth and teeth

  • Digest food

  • Protect the teeth from decay

There are three pairs of major salivary glands:

  • Parotid glands: The parotid glands are the largest salivary glands. They are located in front of and below the ears.

  • Submandibular glands: The submandibular glands are located below the jaw.

  • Sublingual glands: The sublingual glands are located under the tongue.

Vectorized image of the salivary glands.

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Common symptoms of Salivary Gland Dysfunction can include:


  • Dry mouth or xerostomia

  • Swelling and pain in the cheeks or neck

  • Difficulty swallowing (dysphagia)

  • Increased dental problems

  • Bad breath (halitosis)

  • Changes in taste


Several things may cause the dysfunction of salivary glands including:

  • Salivary Gland Infections - Infections, such as viral infections (e.g., mumps) or bacterial infections, can affect the salivary glands and temporarily reduce saliva production.

  • Salivary Stones - Salivary gland stones or sialolithiasis can block the ducts that carry saliva into the mouth, causing pain, swelling, and reduced salivary flow.

  • Autoimmune Disorders - Conditions like Sjögren's syndrome and IgG4-related disease can lead to chronic inflammation and damage to the salivary glands, affecting their function.

  • Radiation Therapy - Radiation therapy for head and neck cancers can damage the salivary glands, leading to reduced saliva production and dry mouth (xerostomia).

  • Medications - Some medications, including antihypertensives, anticholinergics, and antidepressants, can cause reduced salivary flow as a side effect.

  • Dehydration - Dehydration can temporarily reduce saliva production.


Here are some tips for managing salivary gland dysfunction at home:

  • Drink plenty of fluids throughout the day.

  • Chew sugar-free gum or candy to stimulate saliva production.

  • Use a humidifier in your bedroom at night.

  • Avoid smoking and excessive alcohol consumption.

  • Eat a healthy diet and avoid sugary foods and drinks.

  • Brush and floss your teeth regularly.

  • See your dentist for regular checkups and cleanings.


The treatment of salivary gland dysfunction depends on the underlying cause:

  • Infections: Antibiotics may be prescribed for bacterial infections, and supportive care is provided for viral infections.

  • Salivary Stones: Treatment may involve measures to dislodge or remove the stone, such as warm compresses, massaging the gland, or in some cases, surgical removal.

  • Autoimmune Disorders: Management may include immunosuppressive medications to reduce inflammation and protect the salivary glands.

  • Radiation-Induced Dysfunction: Managing dry mouth in individuals who have undergone radiation therapy may involve saliva substitutes, medication adjustments, and dental care to prevent complications.

  • Medication-Induced Dysfunction: If medication side effects are causing reduced salivary flow, the healthcare provider may adjust the medication or recommend saliva-stimulating products.

  • Hydration: For cases of dehydration-related salivary gland dysfunction, increasing fluid intake and maintaining good hydration can be helpful.


Patients with persistent symptoms of salivary gland dysfunction should consult a healthcare provider, preferably a dentist or an ear, nose, and throat (ENT) specialist, for a thorough evaluation and appropriate management. Managing the underlying cause is essential to alleviate symptoms and prevent complications associated with reduced saliva production.

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